My boss needed a new CAD/rendering workstation, but didn't want to sacrifice valuable desk real estate for a tower. She's transitioning from an iMac, so this was an understandable concern. I offered a compromise: bleeding edge performance in a case the size of a shoebox. She liked the idea so I made it happen! Enjoy my latest creation, Espresso Shot.
Edit: I thought I'd talk about my choice of CPU cooler in relation to this motherboard for anyone else looking to go this route. Using a liquid AIO is tempting, but I read the tight space puts unnecessary strain on the socket with all the tubing stuffed in there. I could overclock the chip if I added a second fan on this air cooler and relocated the M.2 to the rear of the motherboard, as the front M.2 riser card would interfere with the extra fan. This is probably the best cooler for professional use to choose for this case at the moment.